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Ana Light range

Bio200

AnaLight Bio200

Accessible, Quantitative Biomolecular Structure-Function Measurement

The AnaLight Bio200 is designed to bring DPI's unique biomolecular structure-function measurements into development and discovery research facilities with a range of biophysical applications.

The AnaLight Bio200 is a "molecular microscope" whose quantitative structural measurements can be compared directly with complementary techniques such as X-ray crystallography, circular dichroism and NMR spectroscopy, whilst also being capable of affinity and kinetic mass measurements at higher sensitivity than first-generation optical or acoustic biosensor technologies.

Key features:

	Twin flow cells give simultaneous, parallel sample analysis for control and comparison
	Independent sample loading and flow rate control to each flow cell
	Software controlled sample injection and flow control for flexibility and precision at low volumes
	Simultaneous measurement on three channels gives total confidence in data integrity
	Wide dynamic range extends solvent (e.g. DMSO) and buffer handling capabilities
	Accurate temperature control and rapid temperature stabilization
	Flexible range of analytical surfaces and reagents available to suit all applications
	Simple upgrade path to fully automated AnaLight BioFlex
	Real-time display of all measurements gives rapid data analysis and streamlined method development

Key Functions:

	Instantaneous, quantitative measurement of biomolecular dimensions, fold density (RI) and mass on two parallel measurement channels
	Software gives option of automated reference channel subtraction when running parallel control experiments
	AnaLight software provides comprehensive analysis of mass changes, affinity, interaction kinetics and structural behaviour in quantitative units
	Measures conformational changes in biomolecules as small as 0.1 Ångstrom as they happen, with or without any mass change
	Wide dynamic range extends solvent (e.g. DMSO) and buffer handling capabilities
	Measures mass changes as low as 0.1 picogram/mm2 in real time, giving class-leading kinetic performance
	Provides a unique information set on the behaviour and interactions of biomolecules with industry-leading resolution
	Automated AnaChip and buffer calibration protocols ensure ultimate measurement accuracy.

Consumables



		AnaChips for Biophysics Farfield offers a range of AnaChips suitable for biophysical applications. The most suitable AnaChip surface for any biomolecular immobilization should be assessed according to the properties of the molecule to be immobilized and the objectives behind the measurements being taken on the AnaLight.