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Farfield AnaLight range
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AnaChip for Surface science applications
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| Surface Science and thin film applications are studied on AnaLight instruments by injecting one or more molecular species into the flow over the prepared surface of an AnaChip, often with another interacting molecule already immobilized. Molecular immobilization onto the AnaChip surface can be undertaken by either covalent chemistry or charge (physisorption).
Farfield offers a range of AnaChips suitable for surface science and Nanotechnology applications. The most suitable AnaChip surface for any experiment should be assessed according to the properties of the molecules being studied and the objectives behind the measurements being taken on the AnaLight.
Farfield offers a comprehensive range of AnaKit consumables to ensure our customers can easily and quickly choose the most suitable combination of capture surface and linker chemistry to succeed in their experiments. This powerful combination means that molecules of any charge or solvation state can be studied at any pH, in any buffer and/or organic solvent that matches the requirements of the analysis.
Further technical information on biophysical immobilization strategies can be found in the Knowledge Base.
AnaChips available for Surface science applications are:
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New Cellulose AnaChip
Surface: Uniform coating of unmodified, dissolving pulp cellulose. Spin coated from NMMO-DMSO solution to give a 17nm thin cellulose surface film. Mimetic surface for cotton-based fabrics and paper. Stable across a range of pH and no loss of surface material in surfactant solution.
- Use: Suitable for fabric care cleaning and conditioning formulation development, paper coating technology and ink formulation studies and pharmaceutical formulation research and development.
- Ordering information: Supplied in packs of 5.
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Unmodified AnaChip
Surface: Unmodified silicon oxynitride giving hydroxyl surface chemistry carrying negative charge. Positively charged molecules can be immobilized to the surface by physisorption. Hydroxyl surface chemistry is also available for customer-defined covalent immobilizations using silane chemistry with or without linkers.
- Use: Suitable for study of proteins from low to high molecular weight, peptides, carbohydrates, lipids, and liposomes.
- Ordering information: Supplied in packs of 5.
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Certified Unmodified AnaChip
Unmodified AnaChip (as above) additionally supplied with Manufacturers Test Certificate guaranteeing specifications and traceability. For use in AnaLight Qualification Procedures and validated applications, where traceability to national and international standards is required.
- Use: Suitable for study of proteins from low to high molecular weight, peptides, carbohydrates, lipids, and liposomes.
- Ordering information: Supplied in a pack of 1.
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Amine AnaChip
Surface: Amine functionalized surface. The first choice for covalent immobilization of biomolecules. Couple to amine groups on the AnaChip surface via -NH2, -CHO or -SH groups on target biomolecule, using one of a range of linker chemistries. Amine surface also carries positive charge, allowing the immobilization of negatively charged biomolecules by physisorption.
- Use: Suitable for study of proteins from low to high molecular weight, peptides, nucleic acids, carbohydrates, lipids, and liposomes.
- Ordering information: Supplied in packs of 5.
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Thiol AnaChip
Surface: Thiol functionalized surface for covalent immobilization of biomolecules. Couple to thiol groups on the AnaChip surface via -NH2 or -SH groups on target biomolecule, with or without linker chemistry. Thiol surface also suitable for the physisorption of more hydrophobic molecules.
- Use: Suitable for study of DNA, RNA, proteins from low to high molecular weight, peptides
- Ordering information: Supplied in packs of 5.
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C18 AnaChip
Surface: C18 hydrocarbon functionalized surface for adsorption of hydrophobic biomolecules, usually those associated with membrane environments. Can also be used for the adsorption of lipids to form hemibilayers as membrane mimics.
- Use: Suitable for adsorption of hydrophobic proteins and peptides and forming lipid-based mimics for membrane protein studies.
- Ordering information: Supplied in packs of 5.
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