Biotechnology attempts to make biology work through the application of technologies such as Photon Correlation Spectroscopy. Improvements in drug efficacy, yield and quality have all benefited from the application of biotechnology.
Once a new active compound is identified there is still a long road ahead to the local pharmacist’s shelf. The delivery mechanisms form an important part of understanding the release to the targeted object. Efficient product screening is necessary to extend the life cycle of any pharmaceutical product and ensure reliable performance.
For large scale production thorough understanding of the process can increase throughput and yield, to ensure that a stable, well characterized biological reaches the customer.
Major concerns are:
Using Photon Correlation Spectroscopy to Improve Drug Delivery Mechanisms
The characterization of a drug delivery system in terms of its size and charge can give valuable information regarding its suitability as a product and may also be used to modify its formulation to increase its efficacy.
Using Photon Correlation Spectroscopy to Improve Product Screening
Development and quality control are concerned with cost-effective screening for optimizing the output of an improved and consistent product performance. Particle size characterization can lead to faster success in the development of consistent, predictable product performance. The Zeta potential is a quick indicator of dispersion stability of pharmaceutical formulations.
Applying Photon Correlation Spectroscopy to Improve Process Yield
During the production process small changes in the solution condition may significantly influence process yield and overall efficiency. Monitoring and identifying the best process conditions can notably increase process throughput, have considerable financial impact and boost the bottom line.
Using Photon Correlation Spectroscopy to Improve Product Stability
Many pharmaceutical products are formulated as suspensions or emulsions. Shelf life and batch-to-batch consistency are important parameters that determine the success and suitability of a product. Particle size and zeta potential measurements can provide the relevant information to determine product stability.
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